Episode 1 - Grampa Pygmalion

Grandpa arranges for Tilda Hicks from Smokey Corners to join the McCoy family as housekeeper, and she immediately sets her cap for widower Luke McCoy. The arrangement proves highly successful until Tilda attends the neighborhood dance with Luke and scores an immediate hit with the local masculine populace.

Episode 2 - Three Strikes and Out

Grandpa becomes romantically entangled with three matrimonially inclined widows when he encourages their interest just enough to promote some free housecleaning chores and a few well-laundered shirts. Luke and Pepino take a dim view of his scheme when it becomes apparent that the three marriage-minded women are literally doing all the McCoy housework in separate shifts.

Episode 3 - Army Reunion

George MacMichael's big moment during his election as commander of the local VFW post is shattered when Grandpa brings to the ceremonies three of George's buddies who know the real story of his ""heroic"" battlefield actions.

Episode 4 - The Roofing Salesman

The wiles of a smooth-talking saleswoman embroil Luke in a roofing paint swindle that involves several of the McCoys' neighbors. Luke soon finds himself in such an embarrassing predicament that he needs the help of Grandpa to rescue him from it.

Episode 5 - The Good Will Tour

Grandpa becomes involved with diplomatic relations and the U.S. State Department when a foreign nation's farm tour visits neighbor George's ranch and Grandpa pursuades the group to detour by the McCoy farm. At first it appears Grandpa has committed a colossal faux pas, but his apparent blundering develops unexpected consequences.

Episode 6 - Money From Heaven

Grandpa thinks he has discovered a gold mine in the sky when an Army paratrooper lands with destructive force on a dilapidated chicken coop that was already marked for the scrap heap. When an Army captain arrives to assess the damages, Grandpa paints a black picture. Luke, however, takes a dim view of Grandpa's shenanigans and bluntly tells him so.

Episode 7 - Actress in the House

Taina Engstrom, a Hollywood actress escaping from her hectic existence, finds peace and quiet at the McCoy farm and discovers that Luke has developed a strong attachment to her. Grandpa grasps the true situation and plans, with Tiana, to prevent Luke from receiving a major disappointment.

Episode 8 - The New Housekeeper

Grandpa proves an easy target for Mrs. Gaylord, an ambitious housekeeper who hopes her new position in the McCoy household may lead to a more permanent position for her unmarried daughter. The daughter, Mary, turns out to be an extremely healthy specimen who immediately makes a play for Luke.

Episode 9 - Pepino's Inheritance

Grandpa and Luke are left with an unproductive hired helper when Pepino apparently inherits a valuable Arizona estate. He warms up his romance with an old girlfriend and brings a flood of salesmen to his doorstep.

Episode 10 - The Girl Veterinarian

Afraid that Grandpa will disapprove, Luke pretends that the girl veterinarian secretly treating their ailing cow is one of his new girlfriends. When Grandpa learns that Luke's ""romance"" is actually only trying to cure Agnes, the sick cow, he explodes, ordering the girl off his property.

Episode 11 - The Health Addict

Luke lands the enjoyable job of teaching calisthenics at a ladies' health club. Grandpa decides that Luke's presence there may attract some business for the McCoy roadside fruit stand. Grandpa then surreptitiously tempts the dieting health club enrollees with a variety of tasty fruit products, thus undermining the efforts of unsuspecting Luke.

Episode 12 - The Love Bug Bites Pepino

Grandpa and George take turns at playing Cupid when their respective farmhands, Pepino and Pedro, find themselves competing for the same girl. Grandpa steps into the romantic triangle because it turns out that Pepino's working efficiency suffers as he loses favor with his girlfriend, Chiquita.

Episode 13 - Luke the Reporter

Luke feels he has discovered a new source of income when he reports the gossip he overhears at the laundromat to the reporter of the local newspaper and is paid for the items. He runs into trouble with Pat Clemens, who runs a local gas station, when he reports that Pat is getting married.

Episode 14 - The Farmer and Adele

A winsome dance instructor tricks Luke into signing up for a 20-year dance course. It is up to Grandpa to rescue him from this embarrassing situation with a devious plan that involves Grandpa's signing up for the course, too. He also saves George, who likewise was tricked into taking the course.

Episode 15 - The Crop Duster

Luke gets a hair-raising ride in an airplane that leaves him dizzy when he tangles with a crop duster over the affections of a wealthy girl from Texas, and winds up on the short end.

Episode 16 - Cupid Wore a Tail

Luke discovers a new romance when he meets an attractive widow, Louise Howard, after her runaway cow tramples the McCoy cornfield. Grandpa connives to promote a romance between Luke and Louise in a most surprising way.

Episode 17 - The Other Side of the Fence

Grampa picks a peck of trouble when he helps Louise harvest her crop. Louise: Janet De Gore. Pepino: Tony Martinez. Luke: Richard Crenna. Grampa: Walter Brennan.

Episode 18 - Sir Fergus McCoy

Grandpa bristles at Sir Fergus, head of the Scottish branch of the McCoy family, when he arrives and proceeds to exercise all the authority of the Laird of the Clan. Grandpa's anger erupts when Sir Fergus extends his influence to Grandpa's pet goose, Floyd. Grandpa begins one of his devious plots to oust the Scotch usurper from his position of power.

Episode 19 - The Little Boy Blew

Little Greg leaves home when his widowed mom decides to remarry. Greg: Butch Patrick. Luke: Richard Crenna. Louise: Janet De Gore.

Episode 20 - Luke in the Ivy League

Episode 21 - Aunt Win Arrives

Aunt Win uses feminine trickery while campaigning for Grampa. Aunt Win: Joan Blondell. Grampa: Walter Brennan.

Episode 22 - Aunt Win's Conquest

Episode 23 - Grampa Apron Strings

Episode 24 - Aunt Win Steps In

Episode 25 - How're You Gonna Keep 'Em Down on the Farm?

Luke and Louise feel they have a real problem with Greg, who is addicted to telling fantastic stories about imaginable playmates and people. When they return home from a day's outing, after leaving Greg with Pepino, he tells them three escaped convicts had been captured by the police at their home, and they decide it is just another one of his tall tales.

Episode 26 - Luke the Dog Catcher

Dog catcher Luke ends up with a houseful of homeless pups. Luke: Richard Crenna. Grampa: Walter Brennan. George: Andy Clyde.

Episode 27 - The Incorruptibles

Episode 28 - The McCoy Hex

When his house begins to rattle, George believes he has been cursed. Karen: Aneta Corsaut. Grampa: Walter Brennan. George: Andy Clyde.

Episode 29 - Skeleton in the Closet

Episode 30 - Uncle Rightly and the Musical Milker

Uncle Rightly McCoy starts courting Flora, hoping she will finance his musical milker. When Luke informs George that Uncle Rightly is only interested in Flora's money, they decide to step in and break up the romance. Their scheme doesn't quite work out as they had planned.

Episode 31 - Up to Their Ears in Corn

Luke is horrified when Uncle Rightly promotes a corn growing contest at the Grange and is so carried away he volunteers a $500 award to the winner in Grandpa and Luke's name. When Luke learns Uncle Rightly doesn't have the $500, it becomes a major problem of raising the money and saving face with the Grange members, but Rightly solves the problem in an unusual way and comes up with the prize money.

Episode 32 - The McCoy Sound

Episode 33 - Luke Grows a Beard

Episode 34 - The Auction

Episode 35 - The Partners

Episode 36 - The Peacemakers

Episode 37 - Don't Be Nosey

Episode 38 - Pals

Episode 39 - Pepino's Mama

Luke shoots for a fortune by selling Mama Garcia's bean sauce. Luke: Richard Crenna. Pepino: Tony Martinez. George: Andy Clyde.