Episode 1 - Sharkbait

Dr. Robert Bolton had invented a gene-slamming device for peaceful uses until his colleague Dr. Luther Paradigm uses it for his evil purposes. When Dr. Bolton tries to intervene, he ends up gene-slammed into an unseen inhuman creature during the struggle and escapes. While in search of their father, John, Clint, Robert, and Coop are mutated into humanoid sharks by the evil Dr. Paradigm. While adapting to their new looks, the four brothers must avoid being seen.

Episode 2 - Sharkbite

The Street Sharks are on a runaway from the police along with their friends Bends and Dr. Lena. The Street Sharks must find a new place to live in and be safe from society.

Episode 3 - Sharkstorm

Ripster, Jab, Streex, and Slammu must protect their reputations and change the way they are being viewed in Fission City. They must fight Dr. Piranoid as well as finding their father once and for all.

Episode 4 - Shark Quest

Dr. Paradigm captures Big Slammu to control his mind and the Street Sharks must break into Dr. Paradigm's hideout to save their brother.

Episode 5 - Lone Shark

While the Street Sharks are going out for burgers, Dr. Paradigm transforms a squid he has acquired into Killamari who becomes the latest member of the Seaviates. The Sharks have to stop them from breaking into the Bolton home and stealing important genetic research data that their father left behind.

Episode 6 - Shark n' Roll

When a musician called Melvin Kresnik accidentally digests contaminated popcorn and water that was tainted with a gene-slamming chemical, he becomes a mako shark later known as Rox and befriends the Street Sharks. Together, they have to save the concert in town and its attendants from being mutated into more sea creatures through the same way that Rox was mutated.

Episode 7 - Fresh Water Sharks

The citizens of Fission City hear an announcement from Dr. Paradigm that he has invented a vaccine against the gene-slamming formula.

Episode 8 - Shark Treatment

With the help of a mind-control serum, Dr. Paradigm turns Jets Taylor into a killer whale mutant named Moby Lick to be his latest Seaviate.

Episode 9 - Road Shark

When Streex has been captured by Dr. Paradigm, the rest of the Street Sharks alongside Moby Lick take to the roads to rescue him.

Episode 10 - Shark Fight

Rox is back in town for the Fission City Music Awards and plans to play the evidence that would expose Dr. Paradigm's gene-slamming activities.

Episode 11 - Sky Sharks

When his hotel had been previously destroyed by the Street Sharks and no family members to live with, Mr. Cunneyworth allows Dr. Paradigm to gene-slam him with the DNA of an electric eel and a moray eel which transforms him into Repteel. While Repteel is ordered by Dr. Paradigm to steal an advanced supercomputer part for his robotic machine, the Street Sharks take a cruise around the city to find the doctor's new Seaviate's location and put a stop to their evil plans.

Episode 12 - Shark of Steel

The Street Sharks are framed and brought out of hiding by Sharkbot, the robotic machine built by Dr. Paradigm in the last episode. The Street Sharks must once again defend their reputations and take on Sharkbot.

Episode 13 - Shark Source

The Street Sharks discover an underground civilization of mutant crocodiles that happen to know Dr. Bolton after he cured them of their damaged genes. Meanwhile, Dr. Paradigm rebuilds Sharkbot and captures one of the mutant crocodiles.

Episode 14 - Jurassic Shark

Episode 15 - Sir Shark-A-Lot

Episode 16 - Shark to the Future

Episode 17 - First Shark

Episode 18 - Rebel Sharks

Episode 19 - Space Sharks

Episode 20 - A Shark Among Us

Episode 21 - To Shark or Not to Shark

Episode 22 - Eco Shark

Episode 23 - Close Encounters of the Shark Kind

Episode 24 - Satellite Sharks

Episode 25 - Cave Sharks